ModeX Therapeutics, an OPKO Health subsidiary, is a clinical-stage biopharmaceutical company developing next-generation multispecific antibodies and vaccines for cancer and infectious disease. ModeX's modular antibody platforms unite the power of multiple biologic components in a single molecule to create multispecific antibodies with greater versatility and potency to fight complex diseases more effectively than traditional approaches. Our current pipeline includes immuno-oncology candidates against both solid and hematological tumors as well as several of the world's most pressing viral threats. Our founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients.

ModeX Therapeutics is seeking a highly skilled and motivated Senior Scientist / Principal Scientist with expertise in antibody / multispecific antibody therapeutic research and development, as well as gene delivery experience.  Primary responsibilities will be to carry out early research projects, from developing novel antibody therapeutics to evaluating gene-based delivery technologies using in vitro assays and in vivo animal models.

The individual will work in our state-of-the-art laboratory in Weston, MA and will be responsible for experimental planning and execution, data analysis and presentation.  This is an exciting opportunity to be part of a cross-functional team and contribute to the development of next-generation synthetic biological therapeutics in a fast-paced, rapidly growing biotech company with a bold vision. 

Key Responsibilities

• Serve as a key leader in the effort to develop novel multispecific antibody and therapeutic strategy and in vivo gene delivery technologies
• Collaborate effectively as part of interdisciplinary research teams to drive the discovery and development of innovative multispecific biotherapeutics and in vivo gene delivery technologies
• Interpret results and present/communicate with cross-functional colleagues for successful execution and completion of projects
• Stay scientifically current and contribute to the implementation of new technology and instrumentation
• Ensure effective, high-quality, timely and appropriate documentation in electronic laboratory notebooks

Qualifications

• Ph.D. or MD with experience in antibody engineering, multispecific antibody construction/production, gene delivery technology, or related field with excellent track record from academia or industry
  • Senior Scientist I/II requires 5-8+ years of relevant experience and demonstrated success
  • Principal Scientist I requires 12+ years of relevant experience and demonstrated success
• Hand-on experiences in molecular biology, cell biology, in vitro/in vivo gene delivery, cell-based in vitro assays, and reporter assays are essential
• Expertise in molecular biology, cell biology, gene delivery and experiences in vivo models from mice to NHP are highly desirable
• Highly adaptable to a fast-paced work environment and capable to lead independently as well as within project teams.

ModeX Therapeutics is an Equal Opportunity Employer